Calendario

Jornada 113/sep.-17/sep./2021
Monterrey FC (El Krone)1-0Mazatlán FC (Hewani Soccercaps Field)23:00hEl Krone
Jornada 225/sep.-03/oct./2021
Mazatlán FC (Hewani Soccercaps Field)1-0Querétaro FC (Frikilandino Stadio)26/sep.-03/oct./202123:15hHewani Soccercaps Field
Jornada 301/oct.-05/oct./2021
Club Necaxa (Estadio Luis Alves "Zague")1-2Mazatlán FC (Hewani Soccercaps Field)21:45hEstadio Luis Alves "Zague"
Jornada 428/sep.-12/oct./2021
Mazatlán FC (Hewani Soccercaps Field)0-1Puebla FC (Estadio Elquincho)16:00hHewani Soccercaps Field
Jornada 512/oct.-18/oct./2021
Atlas FC (Farol da Saudade)2-0Mazatlán FC (Hewani Soccercaps Field)23:00hFarol da Saudade
Jornada 6
Mazatlán FC (Hewani Soccercaps Field)1-2Juárez FC Bravos (WestfernwehStadion)
Jornada 7
Club Tijuana Xolos (Mosaik Stadium)3-0Mazatlán FC (Hewani Soccercaps Field)
Jornada 8
Mazatlán FC (Hewani Soccercaps Field)1-2Club América (Elloco Stadium)
Jornada 9
Club León FC (Nou Camp La Catedral)2-0Mazatlán FC (Hewani Soccercaps Field)
Jornada 10
Toluca FC (Biondabella Stadio)2-0Mazatlán FC (Hewani Soccercaps Field)
Jornada 11
Mazatlán FC (Hewani Soccercaps Field)0-4Chivas Guadalajara (ANGA Cosmopolitano)
Jornada 12
Pachuca FC (Estadio Santa Costanza)0-3Mazatlán FC (Hewani Soccercaps Field)
Jornada 13
Mazatlán FC (Hewani Soccercaps Field)2-0Pumas UNAM (Estadio El Ocho)
Jornada 14
Atlético Celaya (Wembas Road Arena)2-2Mazatlán FC (Hewani Soccercaps Field)
Jornada 15
Mazatlán FC (Hewani Soccercaps Field)0-1Santos Laguna FC (Saint Genese)
Jornada 16
Tigres UNAL (Estadio Universitario)1-2Mazatlán FC (Hewani Soccercaps Field)
Jornada 17
Mazatlán FC (Hewani Soccercaps Field)1-2Cruz Azul (Cachalots Park)